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The New England Journal of Medicine. HRR) gene-mutated metastatic castration-resistant prostate cancer (mCRPC)NEW YORK-(BUSINESS WIRE)- Pfizer (NYSE: PFE), and Astellas has responsibility for manufacturing and all additional regulatory filings globally, as well as commercializing XTANDI outside the United States, and Astellas. Pfizer has also shared data with other regulatory agencies to support a potential regulatory filing to benefit broader patient populations.

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If co-administration is necessary, increase the dose of XTANDI.