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This issue of PLOS Biology features a collection of articles that offer actionable solutions to help build a more sustainable future. The idea that microorganisms, in particular, can help solve many of our environmental problems is championed by many of. Chief among these is the overapplication of synthetic fertilisers, which pollute downstream waters and contribute to greenhouse gas emissions.

What should I tell my health care provider before I take Adcirca?

They need to know if you have any of these conditions:heart disease or heart rhythm problems, coronary artery disease;

• a recent heart attack (within the past 90 days);
• a recent history (in the past 6 months) of a stroke, or congestive heart failure;
• angina (chest pain), high or low blood pressure;
• liver or kidney disease (or if you are on dialysis);
• a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
• a bleeding disorder such as hemophilia;
• a stomach ulcer;
• retinitis pigmentosa (an inherited condition of the eye);
• a physical deformity of the penis (such as Peyronie's disease).

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